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Basic information of HLA-DRB5 :

Official Symbol of Gene HLA-DRB5
Species Homo sapiens
Entrez Gene ID 3127
Official Full Name major histocompatibility complex, class II, DR beta 5
Also known as DRB5; HLA-DRB5*
Gene Type protein coding
dbXrefs Ensembl:ENSG00000198502 MIM:604776; AllianceGenome:HGNC:4953
Map Location 6p21.32
Variation Type DNA methylation at CpG dinucleotides
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method pyrosequencing,RT-PCR
Disease MS
Disease subtype N/A
Population Canadian
Sample Size 48 benign MS patients / 20 malignant MS patients

Literature information of multiple sclerosis :

Pubmed ID 20394989
Year 2010
Title No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5

Results of multiple sclerosis :

Risk Type Phenotypic risk
Main Result Negative
Result We found no significant effect of DNA methylation across HLA-DRB5 on severity.
Mechanism/Pathway N/A