Basic information of APOE :

Official Symbol of Gene	APOE
Species	Homo sapiens
Entrez Gene ID	348
Official Full Name	apolipoprotein E
Also known as	AD2; LPG; APO-E; ApoE4; LDLCQ5
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613
Map Location	19q13.32
Variation Type	allele
refSNP ID	epsilon4 Allele positive / negative

Sample information of multiple sclerosis:

Detected Sample	leucocytes
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	PPMS
Population	white
Sample Size	50 MS patients / 159 healthy controls

Literature information of multiple sclerosis :

Pubmed ID	10847793
Year	2000
Title	No association between the APOE epsilon4 allele and outcome and susceptibility in primary progressive multiple sclerosis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Negative
Result	No association between the APOE epsilon4 allele and outcome and susceptibility in primary progressive multiple sclerosis.
Mechanism/Pathway	The epsilon class of APOE is involved in lipid transport and plays a part in brain development, synapse repair, and response to neuronal injury.