Basic information of CFH :
| Official Symbol of Gene | CFH |
| Species | Homo sapiens |
| Entrez Gene ID | 3075 |
| Official Full Name | complement factor H |
| Also known as | FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000000971 MIM:134370; AllianceGenome:HGNC:4883 |
| Map Location | 1q31.3 |
| Variation Type | allele-haplotype |
| refSNP ID | Tyr402 |
Sample information of multiple sclerosis:
| Detected Sample | venous blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS,PPMS, SPMS,RPMS |
| Population | N/A |
| Sample Size | 44 MS / 40 HCs |
Literature information of multiple sclerosis :
| Pubmed ID | 26186240 |
| Year | 2015 |
| Title | Serum complement factor H and Tyr402 His gene polymorphism among Egyptians with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There was no significant difference in the frequency of CFH Tyr402 His genotypes and alleles between MS patients and healthy controls. |
| Mechanism/Pathway | Serum CFH is the major fluid-phase regulator of the alternative pathway of C, increasingly recognised as a critical player in many diseases. |
