Basic information of CD58 :
| Official Symbol of Gene | CD58 |
| Species | Homo sapiens |
| Entrez Gene ID | 965 |
| Official Full Name | CD58 molecule |
| Also known as | ag3; LFA3; LFA-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000116815 MIM:153420; AllianceGenome:HGNC:1688 |
| Map Location | 1p13.1 |
| Variation Type | SNP |
| refSNP ID | rs12044852 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | hME SNP typing facility |
| Disease | MS |
| Disease subtype | N/A |
| Population | Canadian |
| Sample Size | the multiplex families comprised of a total of 732 subjects: 211 patients with MS and 521 of their unaffected relatives / 182 Canadian individuals free of neurologic disease |
Literature information of multiple sclerosis :
| Pubmed ID | 19506219 |
| Year | 2009 |
| Title | Risk alleles for multiple sclerosis in multiplex families |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The case– control analysis indicates that risk alleles associated with the CD58 genes are overrepresented in familial MS cases as compared with disease-free control subjects . |
| Mechanism/Pathway | N/A |
