Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	allele
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	whole blood
Sample Detail	N/A
Detected Method	PCR-SSCP and PCRRFLP
Disease	MS
Disease subtype	RRMS
Population	Mexican Mestizos
Sample Size	143 RRMS patients / 377 healthy controls

Literature information of multiple sclerosis :

Pubmed ID	26367070
Year	2015
Title	Presence of the HLADR13 allele among Mexican Mestizos suggests a protective factor against relapsing-remitting multiple sclerosis (RRMS)

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	We found HLA DR 13 was more frequent in healthy controls than in RRMS patients, suggesting a protective factor among Mexican Mestizo population.
Mechanism/Pathway	MHC II type-specific antigens are able to display specific viral epitopes that stimulate a T cell response with the following efficient elimination of the virus. It is possible that in MS patients with the DR 13 allele the efficiency in antigen presentation is able to influence disease progression.