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Basic information of GHRL :

Official Symbol of Gene GHRL
Species Homo sapiens
Entrez Gene ID 51738
Official Full Name ghrelin and obestatin prepropeptide
Also known as MTLRP
Gene Type protein coding
dbXrefs Ensembl:ENSG00000157017 MIM:605353; AllianceGenome:HGNC:18129
Map Location 3p25.3
Variation Type SNP
refSNP ID rs696217,rs1629816,rs4684677

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method real-time PCR
Disease MS
Disease subtype RRMS,PPMS,SPMS,CIS
Population German
Sample Size 776 MS patients / 878 control subjects

Literature information of multiple sclerosis :

Pubmed ID 21664965
Year 2011
Title Polymorphisms in genes encoding leptin, ghrelin and their receptors in German multiple sclerosis patients

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Allele and genotype frequencies did not differ significantly between MS patients and controls.
Mechanism/Pathway Through binding to the growth hormone secretagogue receptor (GHSR), ghrelin is involved in the regulation of energy homeostasis and has also been shown to inhibit inflammatory processes.