Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | allele |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | leucocytes |
| Sample Detail | N/A |
| Detected Method | reverse dot-blot method |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian |
| Sample Size | 375 MS patients were divided into two disability subgroups EDSS 0–5.5 (mild/moderate) versus 6–10 (severe disability) |
Literature information of multiple sclerosis :
| Pubmed ID | 11374095 |
| Year | 2001 |
| Title | HLA-DRB1 and disease outcome in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | HLA-DRB1*15 status was not significantly associated with outcome. When assessing the effect of HLA-DRB1*15 on outcome in the total patient group using logistic regression, including disease duration, gender and age at onset as covariates no significant relationships were noted. |
| Mechanism/Pathway | N/A |
