Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	allele
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	sequence-specific oligonucleotide (SSO) method
Disease	MS
Disease subtype	RRMS,PPMS,SPMS
Population	Norwegian and Swedish
Sample Size	323 Norwegian and 911 Swedish patients

Literature information of multiple sclerosis :

Pubmed ID	17662002
Year	2007
Title	The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients

Results of multiple sclerosis :

Risk Type	Phenotypic risk
Main Result	Negative
Result	There was no significant association between other HLA-DRB1 alleles and disease course.
Mechanism/Pathway	Human leucocyte antigen (HLA) complex on chromosome 6p21 is the only locus that has consistently been shown to be associated with MS.