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Basic information of HLA-A :

Official Symbol of Gene HLA-A
Species Homo sapiens
Entrez Gene ID 3105
Official Full Name major histocompatibility complex, class I, A
Also known as HLAA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000206503 MIM:142800; AllianceGenome:HGNC:4931
Map Location 6p22.1
Variation Type allele
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method sequence-specific oligonucleotide (SSO) method
Disease MS
Disease subtype RRMS,PPMS,SPMS
Population Norwegian and Swedish
Sample Size 286 of the Norwegian and 576 of the Swedish patients

Literature information of multiple sclerosis :

Pubmed ID 17662002
Year 2007
Title The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients

Results of multiple sclerosis :

Risk Type Phenotypic risk
Main Result Negative
Result This study could not identify any significant contribution from HLA-A on the clinical phenotype in MS.
Mechanism/Pathway Human leucocyte antigen (HLA) complex on chromosome 6p21 is the only locus that has consistently been shown to be associated with MS.