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Basic information of IL6 :

Official Symbol of Gene IL6
Species Homo sapiens
Entrez Gene ID 3569
Official Full Name interleukin 6
Also known as CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018
Map Location 7p15.3
Variation Type SNP
refSNP ID rs1800796

Sample information of multiple sclerosis:

Detected Sample blood or saliva
Sample Detail Genomic DNA sample
Detected Method PCR
Disease MS
Disease subtype RRMS,SPMS,PPMS
Population The MS patients were all recruited by the Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene).Healthy controls were recruited from Royal Brisbane and Women’s Hospital or University of Queensland staff.
Sample Size 509 patients/279 controls

Literature information of multiple sclerosis :

Pubmed ID 23202972
Year 2012
Title Interleukin-6 gene promoter-572 C allele may play a role in rate of disease progression in multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result Patients with the 572 GC genotype overall showed a significantly higher median MSSS than did those with the GG genotype.
Mechanism/Pathway N/A