Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	haplotype
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	whole blood
Sample Detail	N/A
Detected Method	an allele-specific PCR amplification method
Disease	MS
Disease subtype	N/A
Population	ongoing Canadian Collaborative Project on the Genetic Susceptibility to MS (CCPGSMS)
Sample Size	a total of 7093 individuals from 1432 families ,includes 2454 individuals with definite MS and 4639 of their unaffected first-degree relatives

Literature information of multiple sclerosis :

Pubmed ID	18433881
Year	2008
Title	Parental non-inherited HLA resistance alleles do not confer protection against multiple sclerosis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Negative
Result	There were no significant differences between maternal and paternal transmission of these alleles to affected and unaffected children and no transmission distortion of these alleles between mothers and fathers to sons and daughters,suggesting that noninherited resistance alleles do not appear to play a role in MS.
Mechanism/Pathway	N/A