Basic information of NECTIN2 :
| Official Symbol of Gene | NECTIN2 |
| Species | Homo sapiens |
| Entrez Gene ID | 5819 |
| Official Full Name | nectin cell adhesion molecule 2 |
| Also known as | HVEB; PRR2; CD112; PVRL2; PVRR2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000130202 MIM:600798; AllianceGenome:HGNC:9707 |
| Map Location | 19q13.32 |
| Variation Type | SNP |
| refSNP ID | rs394221 |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | Public domain databases and SNPSelector were used to identify SNPs from the following five plausible MS candidate genes.Monks—Kaplan quantitative transmission/disequilibrium test (MK-QTDT) |
| Disease | MS |
| Disease subtype | N/A |
| Population | non-Hispanic whites of European descent |
| Sample Size | The US data set consisted of 729 stringently ascertained families of MS patients (542 single-case and 187 multiplecase (multiplex) families) comprising 2874 sampled individuals, of whom 1098 were affected with MS. The UK data set consisted of 811 Caucasian MS patients and one or both of their parents, for a total of 2327 sampled individuals. |
Literature information of multiple sclerosis :
| Pubmed ID | 16738668 |
| Year | 2006 |
| Title | Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | showed significant evidence for an association with MS severity. |
| Mechanism/Pathway | N/A |
