Basic information of HLA-A :
| Official Symbol of Gene | HLA-A |
| Species | Homo sapiens |
| Entrez Gene ID | 3105 |
| Official Full Name | major histocompatibility complex, class I, A |
| Also known as | HLAA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000206503 MIM:142800; AllianceGenome:HGNC:4931 |
| Map Location | 6p22.1 |
| Variation Type | haplotype |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | a commercial kit (LABType SSO Typing Tests),alleles’ detection was done using a non-radioactive PCR-SSOP (polymerase chain reaction-based sequence specific oligonucleotide probe) reverse line-blot assay, |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Puerto Ricans |
| Sample Size | 35 patients and 31 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23767380 |
| Year | 2013 |
| Title | HLA class I & II alleles in multiple sclerosis patients from Puerto Rico |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The OR for HLA-A *30 was 7.2 (95%CI:.74, 70.2) times the odds of having MS in participants classified in the category “othersâ€. This excess was marginally significant (p-value= 0.089). |
| Mechanism/Pathway | N/A |
