Basic information of IL6 :
| Official Symbol of Gene | IL6 |
| Species | Homo sapiens |
| Entrez Gene ID | 3569 |
| Official Full Name | interleukin 6 |
| Also known as | CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018 |
| Map Location | 7p15.3 |
| Variation Type | polymorphisms |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP analysis |
| Disease | MS |
| Disease subtype | RRMS,SPMS |
| Population | Caucasian |
| Sample Size | MS patients(n=131):RR-MS group(n=88), SP-MS group(n=43)/controls(n=157) |
Literature information of multiple sclerosis :
| Pubmed ID | 11574109 |
| Year | 2001 |
| Title | The -174/-597 promoter polymorphisms in the interleukin-6 gene are not associated with susceptibility to multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Negative |
| Result | The -597/-174 IL-6pr genotypes have no major role in susceptibility to MS and in determining the clinical course of the disease or age of onset. |
| Mechanism/Pathway | N/A |
