Basic information of Eae23 :
| Official Symbol of Gene | Eae23 |
| Species | Rattus norvegicus (Norway rat) |
| Entrez Gene ID | 100303366 |
| Official Full Name | Experimental allergic encephalomyelitis QTL 23 |
| Also known as | N/A |
| Gene Type | unknown |
| dbXrefs | discontinued |
| Map Location | 10; 10 16.93 cM |
| Variation Type | allele |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | lymph nodes |
| Sample Detail | at day 7 p.i. from MOG-immunized |
| Detected Method | RT-PCR |
| Disease | EAE |
| Disease subtype | Rats immunized intradermally in the dorsal tail base with recombinant rat MOG (amino acids 1–125 from the N terminus) expressed in Escherichia Coli. |
| Population | MOG-immunized DA and DA.PVG-Eae23 female rats |
| Sample Size | DA(n=10)/DA.PVG-Eae23(n=11) |
Literature information of multiple sclerosis :
| Pubmed ID | 20856809 |
| Year | 2010 |
| Title | Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | N/A |
| Result | No significant differences between the strains were seen in ZEB1, Zfhep1 or IL2,mRNA expression of the splice variant Zfhep2 was higher in DA and a trend of lower secreted IL-2 in DA were observed. |
| Mechanism/Pathway | N/A |
