Basic information of Eae23 :
| Official Symbol of Gene | Eae23 |
| Species | Rattus norvegicus (Norway rat) |
| Entrez Gene ID | 100303366 |
| Official Full Name | Experimental allergic encephalomyelitis QTL 23 |
| Also known as | N/A |
| Gene Type | unknown |
| dbXrefs | discontinued |
| Map Location | 10; 10 16.93 cM |
| Variation Type | allele |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | spleens |
| Sample Detail | on day 35 p.i |
| Detected Method | RT-PCR |
| Disease | EAE |
| Disease subtype | Rats immunized intradermally in the dorsal tail base with recombinant rat MOG (amino acids 1–125 from the N terminus) expressed in Escherichia Coli. |
| Population | MOG-immunized DA and DA. PVG-Eae23 female rats |
| Sample Size | DA(n=9)/DA.PVG-Eae23(n=13) |
Literature information of multiple sclerosis :
| Pubmed ID | 20856809 |
| Year | 2010 |
| Title | Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | N/A |
| Result | The shared region of ZEB1, Zfhep2 and IL2 were significantly up-regulated in DA compared to DA.PVG-Eae23, while Zfhep1 was significantly down-regulated in DA compared to DA.PVG-Eae23. |
| Mechanism/Pathway | N/A |
