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Basic information of MPO :

Official Symbol of Gene MPO
Species Homo sapiens
Entrez Gene ID 4353
Official Full Name myeloperoxidase
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000005381 MIM:606989; AllianceGenome:HGNC:7218
Map Location 17q22
Variation Type myeloperoxidase promoter polymorphism
refSNP ID position 1856–2629 of MPO

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Olmsted County
Sample Size 122 patients with MS ,244 controls

Literature information of multiple sclerosis :

Pubmed ID 10742562
Year 2000
Title Association of a myeloperoxidase promoter polymorphism with multiple q sclerosis

Results of multiple sclerosis :

Risk Type N/A
Main Result N/A
Result We did not find an association with gender, age at onset, susceptibility to, or the course and severity of MS in a population-based sample of 122 patients from Olmsted County
Mechanism/Pathway Myeloperoxidase (MPO) generates hypochlorous acid and other reactive oxygen intermediates leading to tissue damage