Basic information of CTLA4 :
| Official Symbol of Gene | CTLA4 |
| Species | Homo sapiens |
| Entrez Gene ID | 1493 |
| Official Full Name | cytotoxic T-lymphocyte associated protein 4 |
| Also known as | CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000163599 MIM:123890; AllianceGenome:HGNC:2505 |
| Map Location | 2q33.2 |
| Variation Type | Polymorphism of the CTLA-4 gene |
| refSNP ID | dinucleotide microsatelite (AT) |
Sample information of multiple sclerosis:
| Detected Sample | venous blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Polish MS patients |
| Sample Size | n=102 |
Literature information of multiple sclerosis :
| Pubmed ID | 12894875 |
| Year | 2003 |
| Title | Lack of Association between an Exon 1 CTLA-4 Gene Polymorphism A(49)G and Multiple Sclerosis in a Polish Population of the Lower Silesia Region |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | Negative |
| Result | Polymorphism of the CTLA-4 gene (chromosome 2q33) could thus have effects upon the immune response |
| Mechanism/Pathway | the CTLA-4 exon 1 gene polymorphism at position 49, which results in amino acid exchange (Thr to Ala) in the leader sequence10 |
