Basic information of HLA-DQA1 :

Official Symbol of Gene	HLA-DQA1
Species	Homo sapiens
Entrez Gene ID	3117
Official Full Name	major histocompatibility complex, class II, DQ alpha 1
Also known as	CELIAC1, DQ-A1, DQA1, HLA-DQA, HLA-DQA1*, HLA-DQB1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196735 MIM:146880; AllianceGenome:HGNC:4942
Map Location	6p21.32
Variation Type	multiallelic polymorphisms
refSNP ID	DQA1*0102

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	Italian Multiplex Families
Sample Size	28 multiplex MS families,for a total of 59 patients (23 males, 36 females), and 126 clinically healthy relatives (55 males, 71 females)

Literature information of multiple sclerosis :

Pubmed ID	8556305
Year	1995
Title	Evidence of Linkage between Susceptibility to Multiple Sclerosis and HLA-Class II Loci in Italian Multiplex Families

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	MS susceptibility is conferred by HLA class II alleles
Result	Evidence supporting the existence of linkage between MS susceptibility and the HLA class II loci DRB1, DQA1 and DQB1 was provided using two non-parametric tests, affected sib-pair analysis, and affected-pedigree-member (APM) analy- sis.
Mechanism/Pathway	MS susceptibility is conferred by HLA class II alleles according to a low-penetrance autoso- mal recessive mode of inheritance.