Basic information of TNF :
| Official Symbol of Gene | TNF |
| Species | Homo sapiens |
| Entrez Gene ID | 7124 |
| Official Full Name | tumor necrosis factor |
| Also known as | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892 |
| Map Location | 6p21.33 |
| Variation Type | gene polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | southern blotting |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Department of Neurology, University Hospital, Lund, Sweden |
| Sample Size | 41 MS patients with RRMS,21 patients with monosymptomatic optic neuritis |
Literature information of multiple sclerosis :
| Pubmed ID | 1969423 |
| Year | 1990 |
| Title | Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | the frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls. |
| Mechanism/Pathway | N/A |
