Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	allele
refSNP ID	HLA-DRB1*15:01

Sample information of multiple sclerosis:

Detected Sample	blood or saliva samples
Sample Detail	N/A
Detected Method	N/A
Disease	MS
Disease subtype	N/A
Population	the United States, Sweden, and Norway
Sample Size	2,497 female MS cases from 4 cohorts

Literature information of multiple sclerosis :

Pubmed ID	33037103
Year	2020
Title	Pregnancy does not modify the risk ofMS in genetically susceptible women

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	not related
Result	Evidence for interaction between pregnancy exposure and established genetic risk variants, including the strongly associated HLA-DRB1*15:01 allele and a weighted genetic risk score, was not observed. Results from sensitivity analyses were consistent with observed results.
Mechanism/Pathway	N/A