Basic information of LINGO1 :
| Official Symbol of Gene | LINGO1 |
| Species | Homo sapiens |
| Entrez Gene ID | 84894 |
| Official Full Name | leucine rich repeat and Ig domain containing 1 |
| Also known as | LERN1; MRT64; LRRN6A; UNQ201 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000169783 MIM:609791; AllianceGenome:HGNC:21205 |
| Map Location | 15q24.3 |
| Variation Type | SNP |
| refSNP ID | rs11856808 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Oriental or Caucasian descent |
| Sample Size | 293 unrelated Caucasian Spanish patients,318 healthy unrelated Caucasian Spanish individuals gender and agematched with the patients |
Literature information of multiple sclerosis :
| Pubmed ID | 23574883 |
| Year | 2013 |
| Title | LINGO1 rs9652490 and rs11856808 polymorphisms are not associated with risk for multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | not related |
| Result | These results suggest that LINGO1 rs9652490 and rs11856808 polymorphisms are not related with risk for MS. This study adds to other published evidence indicating that, to date, the LINGO1 SNPs studied here could be useful risk biomarkers of developing essential tremor, but not other movement disorders. |
| Mechanism/Pathway | N/A |
