Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | allele |
| refSNP ID | HLA-DRB1*15:01 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Italian |
| Sample Size | 253 208 (133 508 women, 119 700 men) |
Literature information of multiple sclerosis :
| Pubmed ID | 23279712 |
| Year | 2013 |
| Title | Prevalence of multiple sclerosis in Verona, Italy: an epidemiological and genetic study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | with a homogenous distribution across the country. HLA-DRB1*15 is a relevant MS susceptibility locus in the Italian population, possibly with little influence on the occurrence of concomitant autoimmune disorders. |
| Mechanism/Pathway | HLA-DRB1*15 is a relevant MS susceptibility locus in the Italian population |
