Basic information of TYK2 :
| Official Symbol of Gene | TYK2 |
| Species | Homo sapiens |
| Entrez Gene ID | 7297 |
| Official Full Name | tyrosine kinase 2 |
| Also known as | JTK1; IMD35 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000105397 MIM:176941; AllianceGenome:HGNC:12440 |
| Map Location | 19p13.2 |
| Variation Type | SNP |
| refSNP ID | rs34536443 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Nordic |
| Sample Size | 5429 Nordic MS cases and 6167 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 19888296 |
| Year | 2010 |
| Title | A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | negative |
| Result | by mega-analysis of 10642 MS patients, 10620 controls and 2110 MS trios, the association at genome-wide significance level (P录5.08 10 9, OR 0.77) was shown. |
| Mechanism/Pathway | protective |
