Basic information of MOG :
| Official Symbol of Gene | MOG |
| Species | Homo sapiens |
| Entrez Gene ID | 4340 |
| Official Full Name | myelin oligodendrocyte glycoprotein |
| Also known as | BTN6; BTNL11; MOGIG2; NRCLP7 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000204655 MIM:159465; AllianceGenome:HGNC:7197 |
| Map Location | 6p22.1 |
| Variation Type | aminoacid substitution |
| refSNP ID | a G→A transition occurring in exon 3 of the human MOG gene. |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | lymphocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | French |
| Sample Size | 83 unrelated MS patients and 82 unrelated healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 9493637 |
| Year | 1997 |
| Title | Identification of a Val I 45 IIe substitution in the human myelin oligodendrocyte glycoprotein: lack of association with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | no association |
| Result | It is therefore unlikely that the MOG Val 145 lle variant is responsible for genetic susceptibility to MS. |
| Mechanism/Pathway | N/A |
