Basic information of TNFRSF1A :
| Official Symbol of Gene | TNFRSF1A |
| Species | Homo sapiens |
| Entrez Gene ID | 7132 |
| Official Full Name | TNF receptor superfamily member 1A |
| Also known as | FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000067182 MIM:191190; AllianceGenome:HGNC:11916 |
| Map Location | 12p13.31 |
| Variation Type | SNP |
| refSNP ID | rs1800693 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | TaqMan |
| Disease | MS |
| Disease subtype | N/A |
| Population | Korean |
| Sample Size | (79 MS and 99 NMO patients) and 237 normal controls in a Korean population |
Literature information of multiple sclerosis :
| Pubmed ID | 22994200 |
| Year | 2012 |
| Title | Associations of CD6, TNFRSF1A, and IRF8 polymorphisms with risk of inflammatory demyelinating diseases |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | one SNP in CD6 (rs12288280, P = 0.04) and three SNPs in TNFRSF1A (rs767455, rs4149577, and rs1800693, P = 0.01-0.03) were associated with NMO |
| Mechanism/Pathway | were predicted to be binding sites for splicing factors |
