Basic information of KIF5A :
| Official Symbol of Gene | KIF5A |
| Species | Homo sapiens |
| Entrez Gene ID | 3798 |
| Official Full Name | kinesin family member 5A |
| Also known as | NKHC; ALS25; MY050; NEIMY; SPG10; D12S1889 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000155980 MIM:602821; AllianceGenome:HGNC:6323 |
| Map Location | 12q13.3 |
| Variation Type | SNP |
| refSNP ID | rs1678542 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian Spanish |
| Sample Size | in a Caucasian Spanish population of 2864 multiple sclerosis (MS) patients and 2930 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20508602 |
| Year | 2010 |
| Title | The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | Our results, in addition to validating some of these loci as risk factors for MS, are consistent with shared genetic mechanisms underlying different immune-mediated diseases. |
| Mechanism/Pathway | the common and specific associated genes in the different immune-mediated diseases will be crucial in future attempts at shaping the contribution of each pathway to the different disorders and the identification of novel therapies |
