Basic information of ZC3HAV1 :
| Official Symbol of Gene | ZC3HAV1 |
| Species | Homo sapiens |
| Entrez Gene ID | 56829 |
| Official Full Name | zinc finger CCCH-type containing, antiviral 1 |
| Also known as | ZAP; ZC3H2; ARTD13; PARP13; FLB6421; ZC3HDC2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000105939 MIM:607312; AllianceGenome:HGNC:23721 |
| Map Location | 7q34 |
| Variation Type | SNP |
| refSNP ID | rs3735007 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | Taqman |
| Disease | MS |
| Disease subtype | RRMS |
| Population | population from mainland Italy,Sardinia |
| Sample Size | 507 patients (333 females and 174 males) and 523 age- and sex-matched healthy individuals (333 females and 190 males);2,273 patients and 1,917 healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 22319148 |
| Year | 2012 |
| Title | A Trans-Specific Polymorphism in ZC3HAV1 Is Maintained by Long-Standing Balancing Selection and May Confer Susceptibility to Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | The selective pressure is likely to be virus driven; in modern populations, this variant associates with susceptibility to MS, possibly via the interaction with environmental factors. |
| Mechanism/Pathway | via the interaction with environmental factors. |
