Basic information of HS6ST2 :
| Official Symbol of Gene | HS6ST2 |
| Species | Homo sapiens |
| Entrez Gene ID | 90161 |
| Official Full Name | heparan sulfate 6-O-sulfotransferase 2 |
| Also known as | MRXSPM |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000171004 MIM:300545; AllianceGenome:HGNC:19133 |
| Map Location | Xq26.2 |
| Variation Type | SNP |
| refSNP ID | rs950792996 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | X chromosome |
| Detected Method | Diseases 10th Revision (World Health O, 2004) code G42 ，PLINK |
| Disease | MS |
| Disease subtype | N/A |
| Population | UK |
| Sample Size | Genomic data for the X chromosome was obtained from the UK Biobank data field 22,425. |
Literature information of multiple sclerosis :
| Pubmed ID | 35905688 |
| Year | 2022 |
| Title | X-linked genetic risk factors that promote autoimmunity and dampen remyelination are associated with multiple sclerosis susceptibility |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | concurrent disruption of both myelination and immune systems significantly increases the risk of MS onset in women |
| Mechanism/Pathway | myelination |
