Basic information of KIR3DL1 :
| Official Symbol of Gene | KIR3DL1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3811 |
| Official Full Name | killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 |
| Also known as | KIR; NKB1; NKAT3; NKB1B; NKAT-3; CD158E1; KIR2DL5B; KIR3DL1/S1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000167633 MIM:604946; AllianceGenome:HGNC:6338 |
| Map Location | 19q13.42 |
| Variation Type | SNP |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | LABType |
| Disease | MS |
| Disease subtype | N/A |
| Population | African Americans |
| Sample Size | MS patients (N=907) and controls (N=1456) |
Literature information of multiple sclerosis :
| Pubmed ID | 26866467 |
| Year | 2016 |
| Title | The killer immunoglobulin-like receptor KIR3DL1 combination with HLA-Bw4 is protective against multiple sclerosis in African Americans |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The protective effect was observed only in individuals who were not positive for the MS risk allele HLA-DRB1*15:01 |
| Mechanism/Pathway | The observed effect cannot be explained by either a specific HLA-B allele or by linkage disequilibrium with HLA-DRB1 or HLA-A. |
