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Basic information of TRIB2 :

Official Symbol of Gene TRIB2
Species Homo sapiens
Entrez Gene ID 28951
Official Full Name tribbles pseudokinase 2
Also known as C5FW; TRB2; GS3955
Gene Type protein coding
dbXrefs Ensembl:ENSG00000071575 MIM:609462; AllianceGenome:HGNC:30809
Map Location 2p24.3
Variation Type SNP
refSNP ID rs7607490

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method iPLEX Sequenom MassARRAY ,PicoGreen
Disease MS
Disease subtype N/A
Population spanish
Sample Size 2863 MS patients, 2938 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 20944657
Year 2011
Title Replication of top markers of a genome-wide association study in multiple sclerosis in Spain

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Only rs9523762 mapping in the GPC5gene was significantly associated(G allele, P1.6 10 5 ; odds ratio (95% confidence interval)1.23 (1.12–1.44)), supporting a role for this proteoglycan in MS predisposition
Mechanism/Pathway MS predisposition