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Basic information of IL12B :

Official Symbol of Gene IL12B
Species Homo sapiens
Entrez Gene ID 3593
Official Full Name interleukin 12B
Also known as CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000113302 MIM:161561; AllianceGenome:HGNC:5970
Map Location 5q33.3
Variation Type SNP
refSNP ID rs3212227

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method TaqMan technology
Disease CD、MS
Disease subtype N/A
Population white Spaniards
Sample Size 598 patients with CD, 414 with MS and 546 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 18368064
Year 2008
Title IL23R: a susceptibility locus forceliac disease andmultiple sclerosis?

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result There are no differences in IL12B genotypes conditioned by IL23R and vice versa
Mechanism/Pathway increasing susceptibility to CD and MS