Basic information of IL1B :
| Official Symbol of Gene | IL1B |
| Species | Homo sapiens |
| Entrez Gene ID | 3553 |
| Official Full Name | interleukin 1 beta |
| Also known as | IL-1; IL1F2; IL1beta; IL1-BETA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992 |
| Map Location | 2q14.1 |
| Variation Type | SNP |
| refSNP ID | +3954 C/T ;rs1143634 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | IPLEXTM on SEQUENOM MASSARRAY |
| Disease | MS |
| Disease subtype | N/A |
| Population | Italian Caucasian population |
| Sample Size | 160 patients and 251 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20192980 |
| Year | 2010 |
| Title | The interleukin-1 cluster gene region is associated with multiple sclerosis in an Italian Caucasian population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Our findings support the existence of a causative variant for MS within this candidate region in a representative Italian Caucasian population and, in particular, the role of the IL-1 beta ()512 C/T) variant warrants further investigation. |
| Mechanism/Pathway | causative variant |
