Basic information of IL1A :
| Official Symbol of Gene | IL1A |
| Species | Homo sapiens |
| Entrez Gene ID | 3552 |
| Official Full Name | interleukin 1 alpha |
| Also known as | IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000115008 MIM:147760; AllianceGenome:HGNC:5991 |
| Map Location | 2q14.1 |
| Variation Type | SNP |
| refSNP ID | +4845 G/T; rs17561 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | IPLEXTM on SEQUENOM MASSARRAY |
| Disease | MS |
| Disease subtype | N/A |
| Population | Italian Caucasian population |
| Sample Size | 160 patients and 253 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20192980 |
| Year | 2010 |
| Title | The interleukin-1 cluster gene region is associated with multiple sclerosis in an Italian Caucasian population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Our findings support the existence of a causative variant for MS within this candidate region in a representative Italian Caucasian population and, in particular, the role of the IL-1 beta ()514 C/T) variant warrants further investigation. |
| Mechanism/Pathway | causative variant |
