Basic information of IL7R :
| Official Symbol of Gene | IL7R |
| Species | Homo sapiens |
| Entrez Gene ID | 3575 |
| Official Full Name | interleukin 7 receptor |
| Also known as | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000168685 MIM:146661; AllianceGenome:HGNC:6024 |
| Map Location | 5p13.2 |
| Variation Type | SNP |
| refSNP ID | rs6897932 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | WBC |
| Detected Method | TaqMan assays,qRT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | German |
| Sample Size | 1319 MS patients and 910 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 19231135 |
| Year | 2009 |
| Title | Variation in the IL7RA and IL4RA genes in German multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | these results confirm involvement of polymorphisms in the IL7RA and IL2RA genes in MS pathogenesis and suggest that IL9RA variation may primarily affect chronic disease courses. |
| Mechanism/Pathway | differential splicing |
