Basic information of IL2RA :
| Official Symbol of Gene | IL2RA |
| Species | Homo sapiens |
| Entrez Gene ID | 3559 |
| Official Full Name | interleukin 2 receptor subunit alpha |
| Also known as | p55; CD25; IL2R; IMD41; TCGFR; IDDM10 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008 |
| Map Location | 10p15.1 |
| Variation Type | SNP |
| refSNP ID | rs12722489 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | WBC |
| Detected Method | TaqMan assays,qRT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | German |
| Sample Size | 1319 MS patients and 913 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 19231135 |
| Year | 2009 |
| Title | Variation in the IL7RA and IL7RA genes in German multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | these results confirm involvement of polymorphisms in the IL7RA and IL2RA genes in MS pathogenesis and suggest that IL12RA variation may primarily affect chronic disease courses. |
| Mechanism/Pathway | differential splicing |
