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Basic information of IFNG :

Official Symbol of Gene IFNG
Species Homo sapiens
Entrez Gene ID 3458
Official Full Name interferon gamma
Also known as IFG; IFI; IMD69
Gene Type protein coding
dbXrefs Ensembl:ENSG00000111537 MIM:147570; AllianceGenome:HGNC:5438
Map Location 12q15
Variation Type allele
refSNP ID I1(761)*CA12

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method DNA sequencers
Disease MS
Disease subtype N/A
Population USA, Northern Ireland and Belgium
Sample Size 221 patients (64 men and 157 women),442 controls (128 men and 314 women)

Literature information of multiple sclerosis :

Pubmed ID 15674394
Year 2005
Title IFNG polymorphisms are associated with gender differences in susceptibility to multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result Polymorphisms of IFNG may contribute to differences in susceptibility to MS between men and women
Mechanism/Pathway Men carriers of I1(761)*CA13 , which is in strong linkage disequilibrium with the 30(325)*A, have increased susceptibilit