Basic information of Icam1 :

Official Symbol of Gene	Icam1
Species	Mus musculus
Entrez Gene ID	15894
Official Full Name	intercellular adhesion molecule 1
Also known as	CD54; Ly-47; Icam-1; MALA-2
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000037405 AllianceGenome:MGI:96392
Map Location	9 A3; 9 7.69 cM
Variation Type	Differential Isoform Expression
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	spinal columns
Sample Detail	N/A
Detected Method	hematoxylin and eosin
Disease	EAE
Disease subtype	N/A
Population	C57BL/6J
Sample Size	Wild type (n=12) and Icam1tm1Jcgr mice (n=19). B) Wild type (n=10) and Icam1tm1Bay mice (n=16).

Literature information of multiple sclerosis :

Pubmed ID	20371120
Year	2010
Title	Differential ICAM-1 Isoform Expression Regulates the Development and Progression of Experimental Autoimmune Encephalomyelitis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	the alternatively spliced ICAM-1 isoforms are functional, and play key roles during the progression of CNS inflammation and demyelination in EAE
Mechanism/Pathway	with ICAM-1 ligands such as Mac-1.