Basic information of CTLA4 :

Official Symbol of Gene	CTLA4
Species	Homo sapiens
Entrez Gene ID	1493
Official Full Name	cytotoxic T-lymphocyte associated protein 4
Also known as	CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000163599 MIM:123890; AllianceGenome:HGNC:2505
Map Location	2q33.2
Variation Type	SNP
refSNP ID	-658

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	PBMCs
Detected Method	SNaPshotTM Multiplex Kit
Disease	MS
Disease subtype	N/A
Population	southern-European ancestry (Spain and Portugal)
Sample Size	152 healthy individuals,146 patients with MS

Literature information of multiple sclerosis :

Pubmed ID	18691768
Year	2008
Title	Genomic regulation of CTLA4 and Multiple Sclerosis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	We found that the SNP at 658 only acted as a regulatory SNP in patients with MS, suggesting the existence of epigenetic changes due to this disease.
Mechanism/Pathway	N/A