Basic information of HSPA4 :
| Official Symbol of Gene | HSPA4 |
| Species | Homo sapiens |
| Entrez Gene ID | 3308 |
| Official Full Name | heat shock protein family A (Hsp70) member 4 |
| Also known as | RY; APG-2; HSPH2; hsp70; hsp70RY; HEL-S-5a; HS24/P52 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000170606 MIM:601113; AllianceGenome:HGNC:5237 |
| Map Location | 5q31.1 |
| Variation Type | gene polymorphism |
| refSNP ID | hsp70 -2 (+1267 A/G) |
Sample information of multiple sclerosis:
| Detected Sample | Whole blood |
| Sample Detail | PBMCs |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RR,SP |
| Population | Italian |
| Sample Size | 195 patients，548 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24485944 |
| Year | 2014 |
| Title | Are Hsp70 protein expression and genetic polymorphism implicated in multiple sclerosis inflammation? |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | indicating animplication of the G allele ofHSP70-2 gene polymorphism in the development ofMS. |
| Mechanism/Pathway | an inducible chaperon induced under stress conditions |
