Basic information of IL2RA :
| Official Symbol of Gene | IL2RA |
| Species | Homo sapiens |
| Entrez Gene ID | 3559 |
| Official Full Name | interleukin 2 receptor subunit alpha |
| Also known as | p55; CD25; IL2R; IMD41; TCGFR; IDDM10 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008 |
| Map Location | 10p15.1 |
| Variation Type | SNP |
| refSNP ID | rs12722489 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 47,429 MS and 68,374 control |
Literature information of multiple sclerosis :
| Pubmed ID | 35526474 |
| Year | 2022 |
| Title | Genetic biomarkers in multiple sclerosis: An umbrella review of meta-analyses of observational studies |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We also identified that two associations of IL2RA gene (rs2104286 poly颅 morphism [AA vs AG + GG contrast] and rs12722489 polymorphism [C vs T contrast] with MS risk was also graded as suggestive in the main analysis. |
| Mechanism/Pathway | the rs12722489 polymorphism in the IL2RA gene is associated with an increased risk of disease, |
