Basic information of IL4 :

Official Symbol of Gene	IL4
Species	Homo sapiens
Entrez Gene ID	3565
Official Full Name	nterleukin 4
Also known as	BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000113520 MIM:147780; AllianceGenome:HGNC:6014
Map Location	5q31.1
Variation Type	gene polymorphisms
refSNP ID	C/C, T/C, and T/T genotypes of the -590 region of IL-4

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	PBMC
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	100 MS patients and 150 healthy controls

Literature information of multiple sclerosis :

Pubmed ID	22366824
Year	2010
Title	Association of interleukin-4 polymorphisms with multiple sclerosis in southeastern Iranian patients

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	We observed a significant difference in the C/C, T/C, and T/T genotypes of the -590 region of IL-4 between patients with MS and healthy controls (P<.001).
Mechanism/Pathway	We conclude that functional polymorphisms of IL-4 possibly play a crucial role in the pathogenesis of MS.