Basic information of ACE :
| Official Symbol of Gene | ACE |
| Species | Homo sapiens |
| Entrez Gene ID | 1636 |
| Official Full Name | angiotensin I converting enzyme |
| Also known as | DCP; ACE1; DCP1; CD143 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000159640 MIM:106180; AllianceGenome:HGNC:2707 |
| Map Location | 17q23.3 |
| Variation Type | insertion/deletion gene polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Croatian and Slovenian |
| Sample Size | 275 |
Literature information of multiple sclerosis :
| Pubmed ID | 28430710 |
| Year | 2017 |
| Title | Angiotensin-converting enzyme insertion/deletion gene polymorphism and interferon-å°¾ treatment response in multiple sclerosis patients: a preliminary report |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The ACE I/D polymorphism and pretreatment relapse rate accounted for ～26.7% of the IFN-β response variability among the men in the sample |
| Mechanism/Pathway | the negative response to IFN-å°¾ therapy was associated with the ACE-DD genotype in men |
