Basic information of IFNG :
| Official Symbol of Gene | IFNG |
| Species | Homo sapiens |
| Entrez Gene ID | 3458 |
| Official Full Name | interferon gamma |
| Also known as | IFG; IFI; IMD69 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111537 MIM:147570; AllianceGenome:HGNC:5438 |
| Map Location | 12q15 |
| Variation Type | allelic |
| refSNP ID | located in the first intron of the interferon-gamma gene |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Spanish |
| Sample Size | 1307 |
Literature information of multiple sclerosis :
| Pubmed ID | 16430971 |
| Year | 2005 |
| Title | An IFNG polymorphism is associated with interferon-beta response in Spanish MS patients |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | Our results show a very different allelic distribution when patients with relapses were compared with relapse-free patients. |
| Mechanism/Pathway | Interferon-beta is a biological treatment widely used in multiple sclerosis (MS). However, not every patient responds equally well to this therapy |
