Basic information of MEFV :
| Official Symbol of Gene | MEFV |
| Species | Homo sapiens |
| Entrez Gene ID | 4210 |
| Official Full Name | MEFV innate immunity regulator, pyrin |
| Also known as | FMF; MEF; PAAND; TRIM20 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000103313 MIM:608107; AllianceGenome:HGNC:6998 |
| Map Location | 16p13.3 |
| Variation Type | gene variants |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian descent |
| Sample Size | 915 patients and 763 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23325590 |
| Year | 2013 |
| Title | Rare MEFV variants are not associated with risk to develop multiple sclerosis and severity of disease |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | carrying rare variants in MEFV was associated with the development of severe systemic side-effects upon IFN-å°¾ treatment. |
| Mechanism/Pathway | N/A |
