Basic information of IL10 :
| Official Symbol of Gene | IL10 |
| Species | Homo sapiens |
| Entrez Gene ID | 3586 |
| Official Full Name | interleukin 10 |
| Also known as | CSIF; TGIF; GVHDS; IL-10; IL10A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962 |
| Map Location | 1q32.1 |
| Variation Type | SNP |
| refSNP ID | rs3135932 |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Tunisian |
| Sample Size | 103 Tunisian MS patients and 160 control subjects |
Literature information of multiple sclerosis :
| Pubmed ID | 28225209 |
| Year | 2017 |
| Title | Association of the IL-10 receptor A536G (S138G) lossof-function variant with multiple sclerosis in Tunisian patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | our results suggest that S138G loss-of-function polymorphism of the IL-10R1 may be important risk factor in increasing susceptibility to MS. |
| Mechanism/Pathway | loss-of-function variant |
