Basic information of HLA-G :
| Official Symbol of Gene | HLA-G |
| Species | Homo sapiens |
| Entrez Gene ID | 3135 |
| Official Full Name | major histocompatibility complex, class I, G |
| Also known as | MHC-G |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000204632 MIM:142871; AllianceGenome:HGNC:4964 |
| Map Location | 6p22.1 |
| Variation Type | insertion/ deletion |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | leukocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iranic |
| Sample Size | 212patients |
Literature information of multiple sclerosis :
| Pubmed ID | 26711580 |
| Year | 2016 |
| Title | An investigation into the association between HLA-G 14 bp insertion/ deletion polymorphism and multiple sclerosis susceptibility |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | not only HLA-G 14 bp insertion/deletion polymorphism could be associated with expression rate of the HLA-G gene and its plasma level, but also could be considered as a risk factor for susceptibility to MS in our study population. |
| Mechanism/Pathway | xpression rate of the HLA-G gene and its plasma level |
