Basic information of TNF :
| Official Symbol of Gene | TNF |
| Species | Homo sapiens |
| Entrez Gene ID | 7124 |
| Official Full Name | tumor necrosis facto |
| Also known as | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892 |
| Map Location | 6p21.33 |
| Variation Type | gene polymorphisms |
| refSNP ID | 一308Gï¼A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Han nationality of southern Chin |
| Sample Size | 68 MS, 55 patients |
Literature information of multiple sclerosis :
| Pubmed ID | 17160953 |
| Year | 2006 |
| Title | Association among serous and cerebrospinal fluid TNF-α，gene polymorphisms of TNF-αand multiple sclerosis in Han nationality of southern China |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The TNF-ot level in soFIIIII is associated with active MS，but not in the CSF．The gene o p lymorphisms ofTNF-o．一308Gï¼A is not associated with MS in Han nationality of southern China |
| Mechanism/Pathway | gene polymorphisms |
