Basic information of VDR :
| Official Symbol of Gene | VDR |
| Species | Homo sapiens |
| Entrez Gene ID | 7421 |
| Official Full Name | vitamin D receptor |
| Also known as | NR1I1; PPP1R163 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111424 MIM:601769; AllianceGenome:HGNC:12679 |
| Map Location | 12q13.11 |
| Variation Type | gene polymorphisms |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Japanese |
| Sample Size | 77 Japanese patients with ‘conventional’ MS and 95 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 10465499 |
| Year | 1999 |
| Title | Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | he results indicate for the first time an association ofMS withVDRG polymorphism, which may be involved in pathogenesis of MS, or in the linkage disequilibrium of VDRG to another pathogenic gene loci |
| Mechanism/Pathway | exerts an immunosuppressive effect |
