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Basic information of ZFAT :

Official Symbol of Gene ZFAT
Species Homo sapiens
Entrez Gene ID 57623
Official Full Name zinc finger and AT-hook domain containing
Also known as AITD3; ZFAT1; ZNF406
Gene Type protein coding
dbXrefs Ensembl:ENSG00000066827 MIM:610931; AllianceGenome:HGNC:19899
Map Location 8q24.22
Variation Type SNP
refSNP ID rs2229857

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail PBMC
Detected Method PCR
Disease MS
Disease subtype RRMS
Population Arabian
Sample Size 156 patients and 112 healthy volunteers

Literature information of multiple sclerosis :

Pubmed ID 27572828
Year 2016
Title ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result ZFAT was associated with MS in women but not in men
Mechanism/Pathway genetic basis for the genderassociated susceptibility to MS